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IMHSC 2024 Conference Proceedings


Paper No: 47
Paper Title: Heat and Low-Density Lipoprotein Transfer in Healthy Aorta using Two-Way Fluid-Structure Interaction Method


AUTHORS:
Yonghui Qiao School of Power and Energy, Northwestern Polytechnical University, 1 Dongxiang Rd, Xi’an 710129, P.R. China
Kun Luo College of Energy Engineering, Zhejiang University, 38 Zheda Rd, Hangzhou 310027, P.R. China
Jianren Fan College of Energy Engineering, Zhejiang University, 38 Zheda Rd, Hangzhou 310027, P.R. China

ABSTRACT:
This study aims to reveal the mechanism of heat and low-density lipoprotein (LDL) transfer in healthy aortas leveraging a fluid-structure interaction model. Two healthy aortic geometries are reconstructed. The pulsation and non-Newtonian viscosity of blood flow are considered. The aortic wall is assumed to be hyperelastic. Results show that there is a strong positive correlation (>0.596) between the LDL and wall temperature. The long relative residual time region also coincides with the high LDL, which negatively correlates with wall shear stress and topological shear variation index. This study would inform novel strategies to measure LDL concentration and regulate its accumulation.

Keywords: Computational Hemodynamics, Temperature Distribution, Atherosclerosis

Conference Venue: Male, Maldives
Conference Date: 5-7 November 2024

ISBN Number: 978-625-00-7517-3
DOI Number: https://doi.org/10.53375/imhsc.2024.47


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